11 PhD positions (m/f/d) DFG-funded Research Training Group 2989 (GRK2989)

The University Hospital Essen offers first class medical services in the Ruhr metropolis. Every year, 225.000 patients are treated in 30 clinics, 27 institutes and specialized centers. The over 8.000 employees offer medical care with state-of-the art diagnostics and therapies, which meet highest international standards. Patient care is connected with basic and translational research at an internationally competitive level.

PhD student in preclinical hematology research (m/f/d)

(pay grade: 13 TV-L / 65% – temporary employment)

APPLICATION AREA: Department of Hematology and Stem Cell Transplantation
JOB-ID: 10043

START: At the next possible date
SCOPE: Part time; 25,025 hours
CONTRACT TYPE: Temporary employment
LIMITATION: For a period of 3 years from recruitment

Activities and responsibilities

• Investigation of the mechanisms of immune suppression by CLL cells
• Planning, conduction and analysis of in vivo and in vitro experiments
• In vivo immunization and infection assays
• Flow cytometric analyses
• Bulk and single cell transcriptomic analyses
• Multiplex immunofluorescence imaging
• Supervision of undergraduate students, presentation of scientific results

Qualification profile

• Completed Diploma or master degree in natural sciences
• Ability to work in teams
• Fluent in English, ideally basic command of the German language
• Self-motivated, creative and proactive
• Experience in standard laboratory techniques (immunoblotting, flow cytometry, PCR)
• Experience with in vivo research is a plus
• Experience with R and/or python is a plus
• Experience with spatial transcriptomics or multidimensional imaging data is a plus

We offer

• The DFG research grant “Mechanisms of humoral immunodeficiency in CLL” which aims to elucidate the mechanisms of suppression of the humoral immune response by the malignant cells
• The project is a collaborative effort between our working group and the group of Prof. Dr. Ralf Küppers
• A friendly, collaborative and motivated work environment
• The freedom to realize own research ideas
• Access to in vivo model systems and leading-edge technology platforms
• Great opportunities for scientific collaboration with leading researchers
• Support in obtaining the necessary qualifications for an academic career
• A secure job in the public service of the state of NRW
• Fair payment in accordance with the collective wage agreement (TV-L) incl. annual bonus payment and supplementary company pension scheme
• 30 days of vacation per calendar year (for a full-time position)
• Interdisciplinary work with colleagues from other departments
• Working with modern equipment and certified quality standards
• Family-friendly corporate culture, e.g. company daycare center, vacation program for school-age children, advice and support from the Employee Service Office in all life situations
• Wide range of training and continuing education opportunities, e.g. at the Training Academy of UK Essen
• Active health management, e.g. company integration management, vaccinations, promotion of sports activities
• Attractive fringe benefits, e.g. reduced-price canteen meals, community events, accommodation in student residences

General conditions

• UK Essen aims to increase the proportion of women in areas where women are underrepresented. They are invited to apply and, in accordance with the LGG, are given priority in the case of equal qualifications.
• Severely disabled applicants and persons of equal status within the meaning of § 2 Abs. 3 SGB IX will be given preferential consideration if they are equally qualified.
• The classification is based on the personal and collective agreement requirements.