Postdoctoral Scientist - Neurobiology - Dr Anne Bertolotti - LMB 1957 - Tenders Global

Postdoctoral Scientist – Neurobiology – Dr Anne Bertolotti – LMB 1957

MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

Postdoctoral Scientist/ Career Development Fellow
Salary Range £32,302 to £35,143 per annum
Fixed term, 3 years
MRC Laboratory of Molecular Biology, Cambridge, UK

The MRC Laboratory of Molecular Biology (LMB) is a research institute within UK Research and Innovation (UKRI). UKRI is an entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at

The position is for a molecular and cell biologist with expertise and track record on signaling.

You will join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consists in targeting eIF2a phosphatases to boost protein quality control capacity (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708–716). Krzyzosiak, A., Sigurdardottir, A. et al., A. (2018). Cell, 174(5), 1216–1228.e19; Schneider K. et al., (2020), Sep 15;32(11):108154, Cell Reports; Pitera, A. et al., (2022). Embo J 41, e109985.)

You will join a strong inter-disciplinary team at the LMB, which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animals models of degenerative diseases.  The team also has an excellent record of innovative basic research leading to applications in medicine.

Further information about the position may be obtained from Dr Anne Bertolotti– email: [email protected]

You will be ambitious and creative. You will have a PhD molecular or cell biology or due to complete doctoral studies within 6 months of applying. Relevant molecular and cell biology experience is required and this must be best attested by at least one impactful publication. Interests in signaling, stress responses and/or neurodegenerative diseases is desirable. It is also essential to have significant publications in this area.

You will enjoy interacting with a dynamic interdisciplinary team sharing a passion for science and a commitment to explore the unknown.

The successful applicant will be awarded a three-year Career Development Fellowship / Postdoctoral training Scheme position. This is a training and development position for a post-doctoral scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills. The MRC LMB has excellent scientific core facilities and training opportunities.

Working for UKRI provides a whole host of benefits including a defined benefit pension scheme and excellent holiday entitlement (40 ½ days including bank holidays and privilege days). You will also have access to employee shopping and travel discounts, on-site sport and social facilities, as well as a salary sacrifice scheme for cycle to work.

Closing date: Monday 31st October 2022

Final appointments will be subject to a pre-employment screening.
The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

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