Global Recruitment of High-level Talents & Postdoctoral Research Fellows in ZCMU

Global Recruitment of High-level Talents & Postdoctoral Research Fellows in ZCMU

Zhejiang Chinese Medical University (ZCMU) is a key university in Zhejiang Province, P. R. China. It was jointly established by the People’s Government of Zhejiang Province, the National Administration of Traditional Chinese Medicine (TCM), and the Ministry of Education of the People’s Republic of China. ZCMU is a modern University located near the south bank of Qiantang River, in the city of Hangzhou, a world-famous tourist destination known for its beautiful scenery and rich cultural heritage. The university now has two campuses covering with the total area exceeding 470,000 square meters.

ZCMU can be historically traced back to 1953. ZCMU is among the first batch of universities in China to recruit and cultivate postgraduates of TCM, and takes the lead among Zhejiang provincial universities eligible of awarding doctoral degrees and establishing post-doctoral research stations. Now, ZCMU is a teaching and research-oriented university with TCM and Chinese Materia Medica as its leading subjects, combined with contemporary life science subjects. ZCMU is presently comprised of 22 schools, 3 directly affiliated hospitals and 4 affiliated hospitals with homogeneous management. ZCMU enrolls over 25,000 full-time students, including over 5,600 doctoral and master degree students, and over 1200 international students.

ZCMU is a national demonstration base for cultivating innovative talents. It has independently cultivated a number of high-level talents, including Members of Chinese Academy of Engineering, National Masters of TCM, National “Ten Thousand Talent Program” Leading Talents, Chief Scientist of the 973 Program, and National Famous Doctors of TCM etc. Currently, ZCMU employs 1,600 faculty and staff, and among them, over 430 with senior professional titles, including Members of the Academia Europaea, Distinguished Professors holding the title of “the Cheung Kong Scholar” awarded by the Ministry of Education of P.R.C, recipients of National Natural Science Funds for Distinguished Young Scholar and of National Science Foundation for Excellent Young Scholar Awards, etc.

ZCMU promotes established and new disciplines with emphasis on scientific technology innovation. ZCMU was within the first batch of Zhejiang provincial universities that have been awarded national key discipline. The Research Fields of ZCMU, including Clinical Medicine, Pharmacology and Toxicology, and Biology and Biochemistry, rank at the top 1% of global ranking based on Essential Science Indicators.

ZCMU has been and will continue to adhere to the motto of “Seek the Origin at High Aspiration”, and the philosophy of “Student-centered, Academics-prioritized”, and commits to building a first-class TCM university characterized by cultural inheritance and innovation. ZCMU is now recruiting high-level talents/faculty (postdoctoral research fellows are also particularly welcome) worldwide with the research fields listed as following (but not limited to): basic medicine, clinical medicine, life sciences, pharmacy, bioinformatics, biomedical engineering, nanomedicine, chemistry, nursing and public health. The following research areas are of particular interest: neuroscience, immunity, cancer translational research, osteology, nephrology, pharmacology, public health and traditional medicine.

 

WORKING ENVIRONMENT

ZCMU fosters a rigorous academic atmosphere and institutional environment. ZCMU provides excellent academic research conditions for you to achieve your professional goals and competitive career development conditions in accordance with relevant national and school policies.

(1) For high-level talents, help to establish innovative research teams; and foster PhD student and postdoctoral fellow enrollment;  

(2) Provide project funding support and opportunities to collaborate with other laboratories with the ZCMU and with the ZCMU Affiliated Hospitals; we strive to provide for a supportive, international and multidisciplinary research environment;

(3) Provide administrative supporting applications for national, provincial, and ministerial scientific research projects.

 

LIVING SECURITY

Income

(1) The annual salary system is implemented and the comprehensive annual salary for national level talents exceeds 700,000 RMB per year (excluding scientific research awards) for high-level talents; exceeds 300,000 RMB per year for postdoctoral fellows.

(2) Health (comprehensive medical) insurance and housing support are also provided;

(3) Income can be discussed on a case-by-case basis.

 

Benefits

(1) Flexible work hours are provided to support family life and priority is given to arranging for children to enroll in child –care, primary schools, junior middle schools and universities;

(2) The ZCMU Affiliated Hospitals provide high-quality medical care;

 

APPLICATION MATERIALS

1. Personal CV

2. Three recommendation letters from acknowledged experts.

Please specify in the subject of the email: NAME + RESEARCH DIRECTION.

 

CONTACT INFORMATION

For High-level talents Address: Human Resources Department, No. 548 Binwen Road, Binjiang District, Hangzhou City, Zhejiang Province, China

Tel: Dr. Sun +86-571-86613616

Email: Sunnylt@zcmu.edu.cn

OFFICIAL WEBSITE ADDRESS: https://www.zcmu.edu.cn/english/index.htm

 

For postdoctoral fellows Please contact postdoctoral supervisor in each lab listed below:

https://mp.weixin.qq.com/s/gYTIFA3Ws0U9UQxnA8mvUQ

 

Please contact international labs (see detailed introduction below)

Cancer Cell Signaling lab (Prof. Georgios Giamas, georgios.giamas@gmail.com or georgios.giamas@zcmu.edu.cn; and CC email to Dr. Zhendong Liu, zjszyyzzrsb@163.com)

SUMO and Ubiquitin Pathways in Genome Stability (Prof. Ivan Psakhye, psakhye.ivan@yahoo.com)

 

 

Opportunities for Postdoctoral Research Fellows – Cancer Cell Signaling lab (Prof. Georgios Giamas Lab)  

Employer: Zhejiang Chinese Medical University (ZCMU)

Location: Hangzhou, Zhejiang, China

Location: Binwen Campus, Hangzhou, Zhejiang

Salary 300,000 CNY annually. Competitive bonus determined by the level of experience, skill set and progress of the applicants.

Closing date: 30/6/2025

Job Type        Postdoctoral

Employment Full time

Qualification  PhD

Sector             Academia

 

Essential criteria for postdoc (PD) posts:

Excellent written/spoken knowledge of English language. PhD in biochemistry, molecular/cellular biology or equivalent field. Track record of first author publications in reputable journals. Advanced skills in biochemistry, molecular/cellular and cancer biology techniques. Commitment to work in a highly competitive field. A demonstrated ability to write scientific papers/grants. Ability to independently drive a research project and analyze data. Ability to work individually on own initiative and without close supervision, and as part of a team. Excellent organizational and oral/written communication skills. Ability to prioritize and meet deadlines. Excellent presentation and IT skills. Keeping accurate and complete records of lab work. Honesty, motivation, creativity, resilience, commitment and a strong work ethic. The Giamas lab at ZCMU (Binwen Campus, Hangzhou-China) invites exceptional postdoctoral researchers to contribute to groundbreaking discoveries in cancer biology and therapy (focusing predominantly on breast and brain tumors, but also other malignancies). Our lab is dedicated to raveling the complexities of cancer progression, metastasis and resistance, with a mission to translate insights into transformative clinical strategies. We are an active, diverse, vibrant research group and provide a stimulating and supportive research environment. We are committed to research excellence and to nurturing scientific careers amongst our trainees and junior faculty.

As a postdoctoral fellow you will:

Lead high-impact projects with access to cutting edge tools and technology (e.g. single-cell sequencing, CRISPR screening, spatial transcriptomics/proteomics, PDX models, and others). Have access to state-of-the art infrastructure, including but not limited to: core facilities for genomics, proteomics, advanced microscopy, flow cytometry. Collaborate with clinicians, bioengineers and data scientists to bridge basic and translational research. Publish in top-tier journals and participate / present at international conferences.  

An overview of research within the Giamas lab can be found at: https://pubmed.ncbi.nlm.nih.gov/?term=giamas&sort=date&size=200 and at https://glare.bio/

 

Please contact Prof. Georgios Giamas (georgios.giamas@gmail.com and georgios.giamas@zcmu.edu.cn) for informal enquiries.

Formal applications should be accompanied by a full CV and the names of three academic referees.  Please send these materials to Prof. Georgios Giamas (georgios.giamas@gmail.com and georgios.giamas@zcmu.edu.cn) and CC email to Dr. Zhendong Liu (zjszyyzzrsb@163.com; Tel: +86-571-87071816).

 

 

 

 

 

 

Opportunities for Postdocs in the laboratory of Ivan Psakhye – SUMO and Ubiquitin Pathways in Genome Stability

 

Employer: Zhejiang Chinese Medical University

Location: Hangzhou, Zhejiang, China

Salary: 300,000 CNY annually plus competitive bonus determined by the level of experience, skill set and progress of the fellow.

Benefits: Medical insurance, campus food allowance and subsidized campus accommodation.

Starting date: July 1, 2025. The starting date is flexible from July 1^st 2025, and applications will be reviewed on a rolling basis until the positions are filled.

Job Type: Postdoctoral

Employment: Full time

Duration: 3 years. The appointment is fully supported for 3 years, after which the position may be further extended if required.

Qualification: PhD

 

Research:

Our newly established laboratory at Zhejiang Chinese Medical University is currently seeking enthusiastic young scientists to join us as postdoctoral fellows. Our aim is to conduct fundamental mechanistic research with a focus on functional aspects related to the SUMO and ubiquitin pathways. Moreover, we have a general interest in DNA replication, DNA repair, sister chromatid cohesion, genome stability and chromatin biology, in particular if ubiquitin family proteins are involved. Because of the available tools for rapid and elegant genetic manipulation, budding yeast Saccharomyces cerevisiae is ideally suited for the mechanistic cell biology studies we conduct in the lab. To extend the significance of the findings made in yeast to a more universal level, key mechanistic insights will be validated also in mammalian cells.

Posttranslational modification (PTM) of proteins by attachment of ubiquitin (ubiquitylation) is best known for its function to label proteins for degradation by the proteasome. However, ubiquitylation plays non-proteolytic roles as well, e.g. for DNA repair, gene expression and signal transduction. Another member of the ubiquitin family, Small Ubiquitin-like Modifier (SUMO), functions primarily in the non-proteolytic (non-proteasomal) manner. It affects protein-protein interactions, interplays with the ubiquitin pathway, controls DNA repair, replication, sister chromatid cohesion and supports genome stability.

Ubiquitin typically targets individual proteins and high selectivity is provided by a plethora of ubiquitin-conjugating enzymes and ligases. Much less is known regarding how modification by the ubiquitin-related protein SUMO influences the function of its targets and how substrate specificity is achieved. Surprisingly, although thousands of proteins are modified by SUMO, only a handful of enzymes participate in the pathway. Moreover, although SUMO modification is essential for viability, mutants defective in SUMOylation of individual substrates typically lack deleterious phenotypes. We previously discovered that SUMOylation operates strategically different from ubiquitylation as it often targets entire groups of proteins that are spatially and functionally connected rather than individual substrates (Psakhye and Jentsch, Cell, 2012). In “protein-group modification” SUMO functions as intermolecular “glue” thereby stabilizing dynamic macromolecular protein complexes and concentrating activities. Thus, the traditional view that a single PTM on a given substrate mediates a specific function does not seem to apply for many SUMO modifications.

In our laboratory, we will focus on the principles of protein-group modification and its special requirements for specificity, formation, timing, and disassembly. We will expand the concept of protein-group SUMOylation with a focus on pathways relevant for cellular physiology, genome integrity in particular, and which are of medical importance. The broad scientific goal of the laboratory will be to advance the understanding of the general mechanisms and functions of the SUMO pathway, and its interplay with other PTM systems.

Below find the examples of the kind of research that we conduct for further reading:

Psakhye and Jentsch, Cell, 2012. DOI: 10.1016/j.cell.2012.10.021

Lu, Psakhye and Jentsch, Cell, 2014. DOI: 10.1016/j.cell.2014.05.048

Psakhye, Castellucci and Branzei, Mol Cell, 2019. DOI: 10.1016/j.molcel.2019.08.003

Psakhye and Branzei, Cell Rep, 2021. DOI: 10.1016/j.celrep.2021.109485

Psakhye et al., Nat Struct Mol Biol, 2023. DOI: 10.1038/s41594-023-01064-x  

 

A few things to consider:

In our laboratory you can work on significant biological questions of general importance. Because our scientific interest is broad, you get in contact with a wide range of biological topics and have the choice of different projects. Our techniques and methods range from yeast genetics, protein biochemistry, cell biology, proteomics, microscopy to whole genome sequencing and advanced genetic and interaction screens. We have many opportunities for international collaborations and English is our working language.  

 

Qualifications:

Applicants should have a strong interest in cell biology or molecular biology and high motivation to uncover the molecular mechanisms. We are conducting basic research and are mainly interested in discovering new cellular functions or principles rather than studying details. Postdoc candidates are expected with a record of successful research in the areas of molecular biology, cell biology, biochemistry, or genetics.

 

How to apply?

To apply, please forward a curriculum vitae, bibliography, and the names and addresses of referees to Prof. Ivan Psakhye: psakhye.ivan@yahoo.com