Post-doc position in cardiac physiology

Organisation/Company

l’institut du thorax, INSERM, CNRS, Nantes Université

Department

the research unit of l’institut du thorax

Research Field

Biological sciences » Biology
Medical sciences » Health sciences

Researcher Profile

First Stage Researcher (R1)
Recognised Researcher (R2)

Country

France

Application Deadline

31 Mar 2024 – 00:00 (Europe/Paris)

Type of Contract

Temporary

Job Status

Full-time

Offer Starting Date

1 May 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The candidate will join Flavien Charpentier’s group within “Ion Channels & Cardiopathies ” research team (led by Michel De Waard & Flavien Charpentier) at the cutting-edge research unit of l’institut du thorax (INSERM, CNRS & Nantes University) in Nantes, France.

L’institut du thorax is a public expert center dedicated to patient care, translational research and training in cardiovascular, respiratory and metabolic diseases. Our laboratory fosters a culture of strong teamwork and supports individual career development.

We are seeking a highly skilled and motivated candidate to contribute to an ANR-funded project, PDEtreat4Heart, focusing on a new therapeutic strategy for heart failure. This collaborative initiative involves our team alongside Jérôme Leroy’s team at Inserm UMR 1180, Faculty of Pharmacy, University Paris-Saclay.

We are looking for a candidate with a strong background and experience in at least one of the following models: engineered heart tissues (EHT) with cardiomyocytes derived from human induced pluripotent stem cells or models of heart failure secondary to ischemia-reperfusion.

The successful candidate will benefit from technical assistance.

The candidate will play a pivotal role in the project management, conducting in vivo and ex vivo experiments, and fostering collaboration within the consortium. Responsibilities will also include presenting results at lab meetings, international congresses, and within the consortium.

Main Activities

• Development of the models
• Functional investigations (contractility, electrophysiology)
• Experiments in biochemistry and immuno-histochemistry
• Playing an active role in supervising students (undergraduate and PhD)

Requirements

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Skills/Qualifications

• Competences in cardiac physiology are mandatory
• Either experience in induced pluripotent stem cell culture and differentiation into cardiomyocytes or in cardiac surgery and functional investigation (echocardiography and/or electrocardiography)
• Experience in immunostaining, molecular biology (qPCR, western blots…)
• Animal testing certification

Specific Requirements

On-call duty in culture room on certain weekends and public holidays

Languages

ENGLISH

Languages

FRENCH

Research Field

Biological sciences

Years of Research Experience

1 – 4

Additional Information

Website for additional job details

https://umr1087.univ-nantes.fr/job-vacancies-internships/job/post-doc-position-…

Work Location(s)

Number of offers available

1

Company/Institute

l’institut du thorax, INSERM, CNRS, Nantes Université

Country

France

City

Nantes

Street

8 quai moncousu

Geofield

Where to apply

E-mail

[email protected]

Contact

City

Nantes

Website

https://umr1087.univ-nantes.fr/

Street

8 quai Moncousu

Postal Code

44000

STATUS: EXPIRED