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We are seeking a highly motivated and self-driven postdoctoral research fellow to advance fundamental research and technology innovation in the field of computational biophysics. This role specifically involves molecular modeling and simulations focused on antibody therapeutics. The ideal candidate will possess a strong motivation to contribute to the development of cutting-edge physics-based and machine-learning techniques to better understand physiochemical stability and developability of complex molecular formats and protein drug products.
Key Responsibilities:
Develop and implement advanced physics-based and machine-learning techniques for practical molecular modeling and simulations of complex biomolecular systems
Investigate the mechanistic aspects of the physiochemical stability of protein drug products.
Integrate basic and applied science, bridging computational modeling with various biophysical experimental techniques.
Collaborate extensively with cross-functional teams in Pharmaceutical Technical Development (PTD) and Genentech Early Research and Development (gRED) departments.
Present and publish research findings to both internal and external scientific communities.
Requirements:
Recent Ph.D. graduate in physics, chemistry, materials science, bioinformatics, computational science, or a related discipline.
Strong understanding of Molecular Dynamics simulations and statistical mechanics fundamentals.
Proficiency in at least one commonly used molecular simulation package such as AMBER, LAMMPS, GROMACS, NAMD, Rosetta, MOE, Schrodinger, Docking tools, and structural rendering tools.
Familiarity with high-performance scientific computing and proficiency in at least one modern computer programming language such as Python, Bash scripting, or C.
Experience with geometric deep learning is a plus.
Effective verbal and written communication skills with a demonstrated ability to collaborate within multi-disciplinary teams.
For information about the Postdoctoral Program at Genentech, please go to:
https://www.gene.com/careers/university-and-early-career/postdocs
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of California is $64,800 and $120,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.
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