Postdoctoral Research Scientist

This opportunity to join the Department of Pediatrics at the Vagelos College of Physicians and Surgeons at the rank of Postdoctoral Research Scientist is an exciting one. Columbia University Irving Medical Center, one of the nation’s foremost academic health science centers. The Department of Pediatrics at Columbia University Irving Medical Center is the top in comparison with other pediatrics department in the NY region in NIH research funding. 

The division of Pediatric Allergy and Immunology in the Department of Pediatrics is seeking a Postdoctoral Research Scientist to join the lab of Dr. Jordan Orange. The candidate in this role will work on a project to explore the molecular mechanisms of cytotoxicity in natural killer (NK) cell and how to exploit the mechanics to potentially optimize cytotoxic cell therapies. This project arises from our ongoing work delineating how lytic granule positioning may impact the efficiency and effectiveness of NK cell killing and how we might intentionally control the mechanics of lytic granules.

Our lab studies molecular mechanisms and cell biology of natural killer (NK) cell cytotoxicity as well as how to exploit these to potentially improve cytotoxic cell therapies. This project arises from our longstanding work delineating the lytic immunological synapse (Nat. Rev. Immunol. 2008 PMID:19172692) and how lytic granule positioning may impact the efficiency and effectiveness of NK cell killing (PLoS Biol 2021 PMID:34343168; J. Immunol 2018 PMID:29592963; Curr Biol 2018 PMID:29398219; J. Cell Biol 2016 PMID:27903610). We are presently pursuing how we might intentionally control the mechanics of lytic granules. 

Recent graduates as well as those who have already completed one post-doctoral fellowship are welcome to apply. Past post-doctoral fellows have gone on to hold faculty positions, various academic roles, and have successful careers in pharma. in Our lab is at the Vagelos College of Physicians and Surgeons Columbia University Irving Medical Center one of the nation’s foremost academic health science centers located in New York City.

Postdoctoral Research Scientist: If you are interested in this position, please apply: http://apply.interfolio.com/149622

Interested candidates should have the required doctorate degree such as MD or PhD with strong experience in Immunology, or cell biology (experience in quantitative imaging, bioinformatics and/or genome editing is preferred).  They should have consistently strong interpersonal skills and the ability to build and sustain effective working relationships with professionals in other disciplines. The ability to create a high-energy results-oriented work environment that encourages colleagues and staff to value each other’s contributions; and the ability to share and celebrate success with colleagues and staff.

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training.  The above hiring range represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

Compensation

Hiring Salary Range: $71,050 – $81,000  

Commitment to Diversity

Columbia University is an Equal Opportunity/Affirmative Action Employer and Educator.  The University is dedicated to the goal of building a culturally diverse and pluralistic faculty and staff committed to teaching and working in a diverse environment, and strongly encourages applications from women, minorities, individuals with disabilities, and veterans. 

Columbia University welcomes applications from individuals who may have had nontraditional career paths, or who may have taken time off for family reasons (e.g. children, caring for disabled or elderly family), or who have achieved excellence in careers outside of academia (e.g., in professional or industry service).  The University is responsive to the needs of dual career couples and is committed to supporting the work-life balance of its faculty.  We are interested in candidates who have a record of success advising and mentoring individuals from groups underrepresented in higher education and is particularly interested in candidates who have research interests in subjects that will contribute to the understanding of diversity and equal opportunity.