Principal Investigator, In Vitro Biology (extensive GPCR experience in highly preferred)

Responsibilities:

• Provide in-depth knowledge and scientific leadership to establish and validate cell-based, molecular, and biochemical assays
• Ensure reliability and reproducibility of screening results and methods, and appropriate data analysis and interpretation to support decision making
• Leverage lab automation to improve assay operation, quality, and overall productivity
• Evaluate and implement new enabling technologies and methods
• Lead early discovery projects from idea conception to proof of mechanism/concept or principle
• Partner with project and functional teams in a matrix environment
• Responsible for effective project management and utilization of internal and external resources.
• Mentor, motivate and develop junior scientists and research associates, contribute to building a positive and results-oriented culture

Qualifications and skills:

• PhD in a life science disciplines with minimal three years of industry experience
• Extensive hands-on experience in establishing novel and standard cell-based, molecular, and biochemical medium/high throughput screening assays
• Hands-on experience with various automated liquid handling instruments and robotic systems for assay operation
• Strong data processing and analysis skills covering single point and dose response analyses
• Experience in independently developing and testing scientific hypotheses based on human disease pathogenesis and drug MOA in various therapeutic areas
• Demonstrated ability to work collaboratively in a cross-functional team environment to advance drug discovery, with excellent organization and communication skills
• Prior experience training, supervising and mentoring associate scientists
• Prior experience with multiple therapeutic modalities (small molecule, peptide, antibody, antibody drug conjugate, etc.) is a plus

Please email your applications to: [email protected]