Staff Research Associate

Cardiovascular Research Inst

Full Time

76511BR

Job Summary

My lab is interested in the general question of how signaling circuits generate complex cellular behaviors such as cell polarity, motility, growth, and differentiation. Because these processes have been difficult to understand with standard techniques, we are developing new approaches to isolate and quantitatively interrogate individual steps in the signaling cascade. 

The ideal candidate will have at least two years of undergraduate experimental research experience and familiarity with mammalian tissue culture and basic molecular biology, and a background in cell biology is a plus.  We are looking for a 2 year time commitment, and candidates ultimately interested in pursing graduate school are encouraged to apply.

The final salary and offer components are subject to additional approvals based on UC policy.

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up): TCS Non-Academic Titles Search (ucop.edu)

Please note: An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The primary mission of the Cardiovascular Research Institute, the largest organized research unit on the San Francisco campus, is to promote fundamental and clinical research on the cardiovascular and pulmonary respiratory systems and to provide opportunities for postdoctoral training in these fields. With over 200 faculty, staff, and postdoctoral fellows, the CVRI supports faculty from a variety of departments (Medicine, Biochemistry, Biophysics, Lab Medicine, Pediatrics, Anatomy, Anesthesia, Pharmaceutical Chemistry, Physiology, Cellular and Molecular Pharmacology). The total extramural funding is $34 million annually (direct and indirect costs), with $1M in indirect cost return, and $561K in State funds. Assets include $38 million in endowment income and gifts, $3M in clinical reserves, and $5.8M in opportunity funds.

Required Qualifications

• BA/BS in a related science and knowledge of, or experience with, the basic techniques or methods required by the position; and/or an equivalent combination of education and experience;
• Some experience in Western Blotting (preparation of biochemical lysates from mammalian cells, polyacrylamide gel electrophoresis, transfer, antibody staining with fluorescence or luminescence-based detection)
• Prior experience working in a research laboratory in an academic environment
• Proven ability to learn new lab procedures
• Advanced light microscopy expertise (TIRF, spinning disc confocal)
• Basic light microscopy knowledge(epifluorescence, DIC)
• Ability to perform Western Blotting (preparation of biochemical lysates from mammalian cells, polyacrylamide gel electrophoresis, transfer, antibody staining with fluorescence or luminescence-based detection)
• Knowledge of Mammalian Cell Culture (Adherent and suspension cell line propagation, freezing, thawing, transient and stable cell transfection)
• Knowledge of  Molecular Biology (DNA Cloning, PCR, Enzymatic assembly)

Preferred Qualifications

• At least 2 years of previous research experience
• Some knowledge Lentivirus generation (293 cell transfection with vector and packaging agents, viral purification, and cell transduction)
• Recombinant protein purification from bacteria
• FACS expertise for analysis and purification of fluorescent cell lines

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Job Code and Payroll Title

009613 SRA 1

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees – Research Support Professionals Unit (UPTE-RX)

Additional Shift Details

M-F, 8-5